A specific counteracting agent called immunoglobin (IgE) causes unfavorably susceptible responses. Antibodies are discharged to battle remote and conceivably unsafe substances in the body. IgE is discharged to annihilate the allergen and causes the generation of synthetic concoctions that trigger the hypersensitive response. One of these synthetic concoctions is called histamine. Histamine causes the fixing of the muscles in the aviation routes and the dividers of veins. It additionally educates the coating of the nose to deliver more bodily fluid.